Angiotensin Converting Enzyme reagent launch
Kinetic method with FAPGG substrate
In the renin-angiotensin system, Angiotensin Converting Enzyme (ACE) catalyzes the conversion of Angiotensin I to Angiotensin II which is found in lungs and in vessels endothelium and increases blood pressure by vasoconstriction and salt and water retention. It also degrades bradykinin, decreasing its vasodilator function.
The measurement of ACE levels in serum is widely used to aid in the differential diagnosis of clinically active pulmonary sarcoidosis and monitoring its treatment with corticosteroids. Its also used for monitoring ACE inhibitors therapy in other disorders such as hypertension, heart failure and diabetic neuropathy.
BioSystems S.A is proud to launch a new ACE reagent (codes 12796 for A15/A25 and 21796 for BA400 and ASR) that measures its concentration in serum or plasma through spectrophotometric kinetic method with FAPGG substrate, which is the preferred method for determination of this marker.